Home > Instruments > EORTC Quality of Life Questionnaire - Core Questionnaire (EORTC QLQ-C30)

EORTC Quality of Life Questionnaire - Core Questionnaire (EORTC QLQ-C30)

The EORTC QLQ-C30 was developed in 1988 and is a core generic questionnaire associated with different disease specific modules


Validated Modules:

Bone metastases EORTC QLQ-BM22

Brain cancer EORTC QLQ-BN20

Breast cancer EORTC QLQ-BR23

Cervical cancer EORTC QLQ-CX24

Colorectal cancer EORTC QLQ-CR29

Colorectal liver metastases EORTC QLQ-LMC21

Elderly Cancer Patients EORTC QLQ-ELD14

Endometrial EORTC QLQ-EN24


Head & Neck cancer EORTC QLQ-H&N35

Hepatocellular carcinoma EORTC QLQ-HCC18

Information EORTC QLQ-INFO25

Lung cancer EORTC QLQ-LC13

Multiple myeloma EORTC QLQ-MY20

Neuroendocrine carcinoid tumours EORTC QLQ-GINET21

Ovarian cancer EORTC QLQ-OV28

Oesophageal cancer EORTC QLQ-OES18

Oesophago-gastric cancer EORTC QLQ-OG25

Prostate cancer EORTC QLQ-PR25



Modules that have completed Phase III:

Chronic Myeloid Leukaemia (QLQ-CML24)     

High-Dose Chemotherapy (QLQ-HDC29)     

Muscle Invasive Bladder Cancer (QLQ-BLM30)     

Ophthalmic Cancer (QLQ-OPT30)     

Breast Reconstruction (QLQ-BrR24)     

Chronic Lymphocytic Leukaemia EORTC QLQ-CLL16

Melanoma (QLQ-MEL38)      

Head & Neck Cancer (QLQ-H&N43)
(revision of QLQ-H&N35)

Cholangiocarcinoma and Gallbladder Cancer (QLQ-BIL21)

Cancer Related Fatigue (QLQ-FA13)

Oral Health (QLQ-OH17)

Pancreatic Cancer (QLQ-PAN26)

Peripheral Neuropathy (QLQ-CIPN20)

Radiation Proctitis (QLQ-PRT23)

Spiritual Wellbeing (QLQ-SWB32)

Superficial Bladder Cancer (QLQ-BLS24)

Testicular Cancer (QLQ-TC26)


Modules in development:

Spinal Cord Compression  

Symptom based questionnaires     

Thyroid Cancer (QLQ-THY)     

Anal Cancer     

Satisfaction with care in outpatients

Nasopharyngeal Carcinoma (QLQ-NPC42)     

Cancer of the Vulva     

Sexual Health

Chronic Lymphocytic Leukaemia (CLL), Non-Hodgkin’s
Lymphoma (NHL) and Hodgkin’s Lymphoma (HL)

Communication (QLQ-COMU34)

Cancer Cachexia

Update of the EORTC QLQ-LC13 Lung module




Access the complete list of modules on the EORTC Quality of Life website


EORTC Quality of Life Group

© Copyright 1995 EORTC Quality of Life Group. All rights reserved. Version 3.0


  • Pathology:


  • Disease:

Generic for Neoplasms

  • Objective:

It has been designed for use in a wide range of cancer patient populations, and is intended to be supplemented by more specific questionnaire modules

  • Population for intended use:




  • Concept of interest:

Health-Related Quality of Life - HRQL (incl. health status)

  • Administration mode:


  • Data collection mode:


Paper and pen

[ Interviewer administration is possible, with the reservation that this should be validated for each questionnaire used in that way ]

  • Type of Clinical Outcome Assessment (COA):

Patient-Reported Outcome (PRO)

  • Number of items:

30 items

  • Recall/Observation period:

During the past week


Bibliographic reference(s) of the original instrument

Aaronson NK, Bullinger M, Ahmedzai S. A modular approach to quality-of-life assessment in cancer clinical trials. Recent Results Cancer Res. 1988;111:231-49

Aaronson NK, Ahmedzai S, Bullinger M, Crabeels D, Estape J, Filiberti AN et al. The EORTC Core Quality of Life Questionnaire : Interim Results of an International Field Study. In: OSOBA D, editor. Effect of Cancer on Quality of Life. Vancouver: 1991: 185-202

Aaronson NK, Ahmedzai S, Bergman B, Bullinger M, Cull A, Duez NJ, Filiberti A, Flechtner H, Fleishman SB, de Haes JC, et al. The European Organization for Research and Treatment of Cancer QLQ-C30: a quality-of-life instrument for use in international clinical trials in oncology. J Natl Cancer Inst 1993; 85:365-76 (PubMed abstract)

Hjermstad MJ, Fossa SD, Bjordal K, Kaasa S. Test/retest study of the European Organization for Research and Treatment of Cancer Core Quality-of-Life Questionnaire. J Clin Oncol. 1995 May;13(5):1249-54 (PubMed abstract)

King MT. The interpretation of scores from the EORTC quality of life questionnaire QLQ-C30. Qual Life Res. 1996 Dec;5(6):555-67. Review (PubMed abstract)

Osoba D, Aaronson N, Zee B, Sprangers M, te Velde A. Modification of the EORTC QLQ-C30 (version 2.0) based on content validity and reliability testing in large samples of patients with cancer. The Study Group on Quality of Life of the EORTC and the Symptom Control and Quality of Life Committees of the NCI of Canada Clinical Trials Group. Qual Life Res. 1997 Mar;6(2):103-8 (PubMed abstract)

Osoba D, Rodrigues G, Myles J, Zee B, Pater J. Interpreting the significance of changes in health-related quality-of-life scores. J Clin Oncol. 1998 Jan;16(1):139-44 (PubMed abstract)

Bjordal K, de Graeff A, Fayers PM, Hammerlid E, van Pottelsberghe C, Curran D, Ahlner-Elmqvist M, Maher EJ, Meyza JW, Brédart A, Söderholm AL, Arraras JJ, Feine JS, Abendstein H, Morton RP, Pignon T, Huguenin P, Bottomly A, Kaasa S. A 12 country field study of the EORTC QLQ-C30 (version 3.0) and the head and neck cancer specific module (EORTC QLQ-H&N35) in head and neck patients. EORTC Quality of Life Group. Eur J Cancer. 2000 Sep;36(14):1796-807 (PubMed abstract)


  • Original language:


  • List of existing translations:

Please refer to Translations tab if available or contact us

To access this information, please sign in or subscribe to PROQOLID database

To access this information, please sign in or subscribe to PROQOLID database

To access this information, please sign in or subscribe to PROQOLID database

To access this information, please sign in or subscribe to PROQOLID database

To access this information, please sign in or subscribe to PROQOLID database

To access this information, please sign in or subscribe to PROQOLID database

Last update: February 2015


For additional information on this instrument, please contact our Information Support Unit


We use cookies to enhance your user experience

By continuing to use our website, you agree to our use of cookies in order to offer you contents and services adapted to your needs.


Free Use Registration Form

In order to use the search options on PROQOLID, please fill out the information below:

Lorem ipsum dolor sit amet, consectetur adipisicing elit. Praesentium delectus aliquid, repudiandae dignissimos ea, aut quas beatae veniam! Libero, provident vel omnis. Hic consequuntur sit, iure fuga assumenda commodi magni!

Thank you!
Your search result is coming...