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National Institutes of Health Stroke Scale (NIHSS)

A modified version of the NIHSS was developed: mNIHSS

Author(s)

NINDS Investigators

Public domain

Purpose

  • Pathology:

Cardiovascular diseases

Nervous system diseases

  • Disease:

Stroke

  • Objective:

To assess neurologic outcome and degree of recovery for stroke patients

  • Population for intended use:

Adult

 

Characteristics

  • Concept of interest:

Physical functioning

Signs and symptoms

  • Administration mode:

Clinician-rated

  • Data collection mode:

Paper and pen

  • Type of Clinical Outcome Assessment (COA):

Clinician-Reported Outcome (ClinRO)

  • Number of items:

NIHSS: 15; mNIHSS: 11

  • Recall/Observation period:

None

 

Bibliographic reference(s) of the original instrument

Albanese MA, Clarke WR, Adams HP Jr, Woolson RF. Ensuring reliability of outcome measures in multicenter clinical trials of treatments for acute ischemic stroke. The program developed for the Trial of Org 10172 in Acute Stroke Treatment (TOAST). Stroke. 1994 Sep;25(9):1746-51

Bulau P, Fuger J, Horn H. [Validating rehabilitation after stroke] Nervenarzt. 1994 Dec;65(12):836-40. German

Lyden P, et al, "Improved reliability of the NIH Stroke Scale using video training. NINDS TPA Stroke Study Group", Stroke. 25(11):2220-6, 1994 Nov

Wityk RJ. Pessin MS. Kaplan RF. Caplan LR, "Serial assessment of acute stroke using the NIH Stroke Scale", Stroke. 25(2):362-5, 1994 Feb

Brott T, Adams HP Jr, Olinger CP, Marler JR, Barsan WG, Biller J, Spilker J, Holleran R, Eberle R, Herztberg V, Rorick M, Moonaw CJ, Walker M. Measurement of acute cerebral infarction: a clinical examination scale. Stroke. 1989;20:864–870

Goldstein LB, Bertels C, Davis JN, "Interrater reliability of the NIH Stroke Scale", Archives of Neurology 46(6)660-2, 1989 June

Bibliographic references of the modified version of the original NIHSS:

Meyer BC, Hemmen TM, Jackson CM, Lyden PD. Modified National Institutes of Health Stroke Scale for use in stroke clinical trials: prospective reliability and validity. Stroke. 2002 May;33(5):1261-6 (full text article)

Lyden PD, Lu M, Levine SR, Brott TG, Broderick J. A modified National Institutes of Health Stroke Scale for use in stroke clinical trials: preliminary reliability and validity. Stroke. 2001 Jun;32(6):1310-7 (full text article)

Language(s)

  • Original language:

English for the USA

  • List of existing translations:

Please refer to Translations tab if available or contact us

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Last update: September 2014

  

For additional information on this instrument, please contact our Information Support Unit

 

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